Statistical & Computational Biology

  • All

    Upcoming

    • Marchi N, Winkelbach L, Schulz I, Brami M, Hofmanová Z, Blöcher J, Reyna-Blanco CS, Diekmann Y, Thiéry A, Kapopoulou A, Link V, Piuz V, Kreutzer S, Figarska S, Ganiatsou E, Pukaj A, Karul N, Gerritsen F, Pechtl J, Peters J, Zeeb-Lanz A, Lenneis E, Teschler-Nicola M, Triantaphyllou S, Stefanović S, Papageorgopoulou C, Wegmann D, Burger J & Excoffier L (2021) The mixed genetic origin of the first farmers of Europe. BioRxiv.
    • Luqman H, Widmer A, Fior S* & Wegmann D (2020) Identifying loci under selection via explicit demographic models. BioRxiv.
    • Žegarac A, Winkelbach L, Blöcher J, Diekmann Y, Gavrilović MK, Porčić M, Stojković B, Milašinović L, Schreiber M, Wegmann D, Veeramah KR, Stefanović S & Burger J (2020) Kinship, acquired and inherited status, and population structure at the Early Bronze Age Mokrin necropolis in northern Serbia. BioRxiv.
    • Louis M, Galimberti M, Archer F, Berrow S, Brownlow A, Fallon R, Nykänen M, O’Brien J, Roberston KM, Rosel PE, Simon-Bouhet B, Wegmann D, Fontaine MC, Foote AD & Gaggiotti OE (2021) Selection on ancestral genetic variation fuels parallel ecotype formation in bottlenose dolphins. BioRxiv.

    2021

    • Ait Kaci Azzou S, Singer L, Aebischer T, Caduff M, Wolf B & Wegmannd D (2021) A sparse observation model to quantify species interactions in time and space. Ecography (in press).
    • Macháček M , Nedoma R, Dresler P, Schulz I, Lagonike, Johnson SM, Kaňáková L, Slámová A, Llamas B, Wegmann D & Hofmanová Z (2021) Runes from Lány (Czech Republic) - The oldest inscription among Slavs. A new standard for multidisciplinary analysis of runic bones. J. Archaeol. Sci (in press)

    2020

    2019

    • Bresadola L, Caseys C, Castiglione S, Buerkle CA*, Wegmann D* & Lexer C* (2019). Admixture mapping in interspecific Populus hybrids identifies classes of genomic architectures for phytochemical, morphological and growth traits. New Phytol 223: 2076-2089.
    • Gros-Balthazard M, Besnard G, Sarah G, Holtz Y, Leclercq J, Santoni S, Wegmann D, Glémin S* , Khadari B* (2019) Evolutionary transcriptomics reveals the origins of olives and the genomic changes associated with their domestication. Plant J 100: 143-157.
    • Leuenberger C & Wegmann D (2019). Statistical Modeling and Inference in Genetics. In Handbook of Statistical Genomics, 4th Edition. Eds. Moltke I & Balding D. Wiley & sons.

    2018

    • Scheib C, Li H, Desai T, Link V, Kendall C, Dewar G, Griffith P, Mörseburg A, Johnson J, Potter A, Kerr S, Endicott P, Lindo J, Haber M, Xue Y, Tyler-Smith C, Sandhu M, Lorenz J, Randall T, Faltyskova Z, Pagani L, Danecek P, O'Connell T, Martz P, Boraas A, Byrd B, Leventhal A, Cambra R, Williamson R, Lesage L, Holguin B, Ygnacio-De Soto E, Rosas J, Metspalu M, Stock J, Manica A, Scally A, Wegmann D, Malhi R & Kivisild T (2018). Ancient human parallel lineages within North America contributed to a coastal expansion. Science 360: 1024--1027.
    • Kousathanas A, Duchen P & Wegmann D (2018). A Guide to General-Purpose ABC Software. In Handbook of Approximate Bayesian Computation. Eds. Sisson SA, Fan Y & Beaumont MA. Chapman and Hall/CRC Press.
    • Veeramah K, Rott A, Gross M, van Dorp L, López S, Kirsanow K, Sell C, Blöcher J, Wegmann D, Link V, Hofmanova Z, Peters J, Trautmann B, Gairhos A, Haberstroh J, Päffgen B, Hellenthal G, Haas-Gebhard B, Harbeck M & Burger J (2018). Population genomic analysis of elongated skulls reveals extensive female-biased immigration in early medieval Bavaria. PNAS (early online).

    2017

    • Gros-Balthazard M, Galimberti M, Kousathanas A, Newton C, Ivorraa A, Paradis L, Vigouroux Y, Carter R, Tengberg M, Battesti V, Santoni S, Falquet L, Pintaud JC, Terral JF & Wegmann D (2017). The discovery of wild date palms in Oman reveals a complex domestication history involving centers in the Middle East and Africa.  Current Biology 27: 2211-2218.e.8.
    • Aebischer T, Siguindo G, Rochat E, Arandjelovic M, Heilman A, Hickisch R, Vigilant L, Joost S & Wegmann D (2017). First quantitative survey delineates the distribution of Chimpanzees in the Eastern Central African Republic. Biological Conservation 213: 84-94
    • Link V, Kousathanas A, Veeramah K, Sell C, Scheu A & Wegmann D (2017). ATLAS: Analysis Tools for Low-depth and Ancient Samples. bioRxiv
    • Duchen P, Leuenberger C, Szilagyi SM, Harmon L, Eastman J, Schweizer M & Wegmann D (2017). Inference of evolutionary jumps in large phylogenies using Lévy processes. Systematic Biology 66(6):950–963.
    • Kousathanas A, Leuenberger C, Link V, Sell C, Burger J & Wegmann D (2017). Inferring heterozygosity from ancient and low coverage genomes. Genetics 205: 317-332.
    • Fonseca Costa SS, Wegmann D & Ripperger JA (2017). Normalisation against circadian and age-related disturbances enables robust detection of gene expression changes in liver of aged mice. PLoS ONE 12(1): e0169615.

    2016

    • Broushaki F, Thomas MG, Link V, López S, van Dorp L, Kirsanow K, Hofmanová Z, Diekmann Y, Cassidy LM, Díez-del-Molino D, Kousathanas A, Sell C, Robson HK, Martiniano R, Blöcher J, Scheu A, Kreutzer S, Bollongino R, Bobo D, Davudi H, Munoz O, Currat M, Abdi K, Biglari F, Craig OE, Bradley DG, Shennan S, Veeramah KR, Mashkour M, Wegmann D, Hellenthal G & Burger J (2016). Early neolithic genomes from the eastern Fertile Crescent. Science 353: 499-503.
    • Hofmanová Z, Kreutzer S, Hellenthal G, Sell C, Diekmann Y, Díez del Molino D, van Dorp L, López S, Kousathanas A, Link V, Kirsanow K, Cassidy LM, Martiniano R, Strobel M, Scheu A, Kotsakis K, Halstead P, Triantaphyllou S, Kyparissi-Apostolika N, Urem-Kotsou DC, Ziota C, Adaktylou F, Gopalan S, Bobo DM, Winkelbach L,Blöcher J, Unterländer M, Leuenberger C, Çilingiroglu Ç, Horejs B, Gerritsen F, Shennan S, Bradley DG, Currat M, Veeramah K, Wegmann D, Thomas MG, Papageorgopoulou C & Burger J (2016). Early farmers from across Europe directly descended from Neolithic Aegeans. PNAS 113: 6886-6891.
    • Kousathanas A, Leuenberger C, Helfer J, Quninodoz M, Foll M & Wegmann D (2016). Likelihood-free inference  in high-dimensional models. Genetics 203(2): 893-904.
    • Ferrer-Admetlla A, Leuenberger C, Jensen JD & Wegmann D (2016). An approximate Markov model for the Wright-Fisher diffusion and its application to time-series data. Genetics 203(2):831-846.
    • Liu Y, Hi Junhua, Li SH, Duchen P, Wegmann D & Schweizer M (2016). Sino-Himalayan mountains act as cradles of diversity and immigration centres in the diversification of parrotbills (Paradoxornithidae).  Journal of Biogeography 43: 1488-1501.
    •  Christe C, Stölting KN, Bresadola L, Fussi B, Heinze B, Wegmann, D, & Lexer C (2016). Selection against recombinant hybrids maintains reproductive isolation in hybridizing Populus species despite F1 fertility and recurrent gene flow. Mol Ecol 25(11):2482–2498.

    2015

    • Bruford MW, Ginja C, Hoffmann I, Joost S, Orozco-terWengel P, Alberto FJ, Amaral AJ, Barbato M, Biscarini F, Colli L, Costa M, Curik I, Duruz S, Feren?akovi? M, Fischer D, Fitak R, Groeneveld LF, Hall SJG, Hanotte O, Hassan F, Helsen P, Iacolina L, Kantanen J, Leempoel K, Lenstra JA, Ajmone-Marsan P, Masembe C, Megens H-J, Miele M, Neuditschko M, Nicolazzi EL, Pompanon F, Roosen J, Sevane N, Smetko A, Štambuk A, Streeter I, Stucki S, Supakorn C, Telo Da Gama L, Tixier-Boichard M, Wegmann D and Zhan X (2015) Prospects and challenges for the conservation of farm animal genomic resources, 2015-2025. Front. Genet. 6:314. doi: 10.3389/fgene.2015.00314.

    2014

    • Adrion JR*, Kousathanas A*, Pascual M, Burrack HJ, Haddad NM, Bergland AO, Machado H, Sackton TB, Schlenke TA, Watada M, Wegmann D* & Singh ND* (2014). Drosophila suzukii: the genetic footprint of a recent, world-wide invasion. Mol Biol Evolution. 31 (12):3148-3163.
    • Dussex N, Wegmann D & Robertson BC (2014). Postglacial expansion and not human influence best explains the population structure in the endangered kea (Nestor notabilis). Mol Ecol 23(9): 2193-2209.
    • Gray M, Wegmann D, Hasl RJ, White MA, Gabriel SI, Searle JB, Cuthbert RJ, Ryan PG & Payseur BA (2014). Demographic history of a recent invasion of house mice on the isolated Island of Gough. Mol Ecol 23 (8): 1923–1939.
    • Foll M*, Poh YP*, Renzette N, Ferrer-Admetlla A, Bank C, Shim H, Malaspinas AS, Ewing G, Liu P, Wegmann D, Caffrey DR, Zeldovich KB, Bolon DN, Wang JP, Kowalik TF, Schiffer CA, Finberg RW, Jensen JD (2014). Influenza Virus Drug Resistance: A Time-Sampled Population Genetics Perspective. Plos Genet. 10(2): e1004185
    • Zawistowski M, Reppell M, Wegmann D, St Jean PL, Ehm MG, Nelson MR, Novembre J & Zöllner S (2014). Analysis of rare variant population structure in Europeans explains differential stratification of gene-based tests. Eur. J. Hum. Genet. 22: 1137-1144.
    • Wegmann D & Currat M (2014). Recipient of the 2013 Molecular Ecology Prize: Laurent Excoffier. Mol Ecol, 23:16-19. 

    2013

    • Chu JH*, Wegmann D*, Yeh CF, Lin RC, Yang XJ, Lei FM, Yao CT, Zou FS & Li SH (2013). Inferring the geographic mode of speciation by contrasting autosomal and sex-linked genetic diversity. Mol Biol Evol. 30: 2519-2530.
    • Schaibley VM, Zawistowski M, Wegmann D, Ehm MG, Nelson MR, St. Jean PL, Abecasis G, Novembre J, Zöllner S & Li JZ (2013). The influence of genomic context on mutation patterns in the human genome inferred from rare variants. Genome Res. 23: 1974-1984.

    2012

    • Slater GJ, Harmon LJ, Wegmann D, Joyce P, Revell LJ and Alfaro ME (2012). Fitting models of continuous trait evolution to incompletely sampled comparative data using Approximate Bayesian Computation. Evolution 66: 752-762.
    • Nelson MR*, Wegmann D*, Ehm MG, Kessner D, St. Jean PL, Verzilli C, Shen J, Tang Z, Bacanu SA, Fraser D, Warren L, Aponte J, Zawistowski M, Liu X, Zhang H, Zhang Y, Li J, Li Y, Li L, Woollard P, Topp S, Hall MD, Nangle K, Abecasis G, Wang J, Cardon LR, Zollner S, Whittaker JC, Chissoe SL, Novembre J and Mooser VE (2012). Abundance of rare functional variants in 202 drug target genes found sequencing 14002 people. Science 337: 100-104.
    • Rubio JP, Topp S*, Warren L*, St. Jean PL, Shen J, Wegmann D, Kessner D, Novembre J, Fraser D, Aponte J, Nangle K, Cardon LR, Ehm MG, Chissoe SL, Whittaker JC, Nelson MR and Mooser VE (2012). Deep sequencing of the LRRK2 gene in 14,002 individuals to guide the clinical development of LRRK2 inhibitors. Hum. Mut. 33: 1087-1098.

    2011

    • Veeramah KR, Tönjes A, Kovacs P, Gross A, Wegmann D, Geary P, Gasperikova D, Klimes I, Scholz M, Novembre J and Stumvoll M (2011). Genetic variation in the Sorbs of eastern Germany in the context of broader European genetic diversity. Eur J Human Genet 19: 995-1001.
    • Stahl EA, Wegmann D, Kraft P, Chen R, Kallberg HJ, Kurreeman FAS, Gregersen PK, Alfredsson L, Siminovitch KA, Worthington J, de Bakker PIW, Raychaudhuri S and Plenge RM (2012). Polygenic modeling of genome-wide association study data reveals hidden heritability of rheumatoid arthritis risk. Nat Genet 44: 483.
    • Veeramah KR, Wegmann D, Woerner A, Mendez FL, Watkins JC, Destro-Bisol G, Soodyall H, Louie L and Hammer MF (2011). An early divergence of KhoeSan ancestors from those of other modern humans is supported by an ABC-based analysis of autosomal re-sequencing data. Mol Biol Evol 29: 617-630.
    • Wegmann D, Kessner D, Veeramah KR, Mathias RA, Nicolae DL, Yanek LR, Sun YV, Torgerson DG, Rafaels N, Mosley T, Becker LC, Ruczinski I, Beaty TH, Kardia SLR, Meyers DA, Barnes KC, Becker DM, Freimer N and Novembre J (2011). Recombination rates in admixed individuals identified by ancestry-based inference. Nat Genet 43:9 847-853.
    • Thalmann O*, Wegmann D*, Spitzner M, Arandjelovic M, Guschanski K, Leuenberger C, Bergl RA and Vigilant L (2011). Historical sampling reveals dramatic demographic changes in western gorilla populations. BMC Evol Biol 11: #85.

    2010

    • Peter B, Wegmann D and Excoffier L (2010). Distinguishing between population bottleneck and population subdivision by a Bayesian model choice procedure. Mol Ecol 19 (21): 4648-4660.
    • Ray N, Wegmann D , Fagundes NJR, Wang S, Ruiz-Linares A, and Excoffier L (2010). A Statistical Evaluation of Models for the Initial Settlement of the American Continent Emphasizes the Importance of Gene Flow with Asia. Mol Biol Evol 27 (2): 337-345.
    • Wegmann D and Excoffier L (2010) Bayesian Inference of the Demographic History of Chimpanzees. Mol Biol Evol 27 (6): 1425-1435.
    • Wegmann D, Leuenberger C, Neuenschwander S and Excoffier L (2010). ABCtoolbox: a versatile toolkit for approximate Bayesian computations. BMC Bioinformatics 11: 116.
    • Leuenberger C* and Wegmann D* (2010) Bayesian Computation and Model Selection Without Likelihoods. Genetics 184 (1): 243-252.

    2009

    • Wegmann D, Leuenberger C and Excoffier L (2009) Efficient Approximate Bayesian Computation Coupled With Markov Chain Monte Carlo Without Likelihood. Genetics 182 (4): 1207-1218.
    • Hofer T, Ray N, Wegmann D and Excoffier L (2009) Large allele frequency differences between human continental groups are more likely to have occurred by drift during range expansions than by selection. Ann Hum Genet 73 (1): 95-108.

    2008

    • Wegmann D, Dupanloup I and Excoffier L (2008). Width of Gene Expression Profile Drives Alternative Splicing. PLoS One 3 (10): e3587.

    2006

    • Wegmann D, Currat M and Excoffier L (2006). Molecular Diversity After a Range Expansion in Heterogeneous Environments. Genetics 174 (4): 2009-2020.


    *order of authroship is arbitrary

  • Conservation

    Upcoming

    • Louis M, Galimberti M, Archer F, Berrow S, Brownlow A, Fallon R, Nykänen M, O’Brien J, Roberston KM, Rosel PE, Simon-Bouhet B, Wegmann D, Fontaine MC, Foote AD & Gaggiotti OE (2021) Selection on ancestral genetic variation fuels parallel ecotype formation in bottlenose dolphins. BioRxiv.

    2021

    • Ait Kaci Azzou S, Singer L, Aebischer T, Caduff M, Wolf B & Wegmannd D (2021) A sparse observation model to quantify species interactions in time and space. Ecography (in press).

    2020

    • Aebischer T, Ibrahim T, Hickisch R, Furrer R, Leuenberger C & Wegmann D (2020). African apex predators decline after an influx of pastoralists in former hunting zones. Biol Cons 241: 108326.

    2017

    • Gros-Balthazard M, Galimberti M, Kousathanas A, Newton C, Ivorraa A, Paradis L, Vigouroux Y, Carter R, Tengberg M, Battesti V, Santoni S, Falquet L, Pintaud JC, Terral JF & Wegmann D (2017). The discovery of wild date palms in Oman reveals a complex domestication history involving centers in the Middle East and Africa.  Current Biology 27: 2211-2218.e.8.
    • Aebischer T, Siguindo G, Rochat E, Arandjelovic M, Heilman A, Hickisch R, Vigilant L, Joost S & Wegmann D (2017). First quantitative survey delineates the distribution of Chimpanzees in the Eastern Central African Republic. Biological Conservation 213: 84-94

    2016

    • Liu Y, Hi Junhua, Li SH, Duchen P, Wegmann D & Schweizer M (2016). Sino-Himalayan mountains act as cradles of diversity and immigration centres in the diversification of parrotbills (Paradoxornithidae).  Journal of Biogeography 43: 1488-1501.
    •  Christe C, Stölting KN, Bresadola L, Fussi B, Heinze B, Wegmann, D, & Lexer C (2016). Selection against recombinant hybrids maintains reproductive isolation in hybridizing Populus species despite F1 fertility and recurrent gene flow. Mol Ecol 25(11):2482–2498.

    2015

    • Bruford MW, Ginja C, Hoffmann I, Joost S, Orozco-terWengel P, Alberto FJ, Amaral AJ, Barbato M, Biscarini F, Colli L, Costa M, Curik I, Duruz S, Feren?akovi? M, Fischer D, Fitak R, Groeneveld LF, Hall SJG, Hanotte O, Hassan F, Helsen P, Iacolina L, Kantanen J, Leempoel K, Lenstra JA, Ajmone-Marsan P, Masembe C, Megens H-J, Miele M, Neuditschko M, Nicolazzi EL, Pompanon F, Roosen J, Sevane N, Smetko A, Štambuk A, Streeter I, Stucki S, Supakorn C, Telo Da Gama L, Tixier-Boichard M, Wegmann D and Zhan X (2015) Prospects and challenges for the conservation of farm animal genomic resources, 2015-2025. Front. Genet. 6:314. doi: 10.3389/fgene.2015.00314.

    2014

    • Adrion JR*, Kousathanas A*, Pascual M, Burrack HJ, Haddad NM, Bergland AO, Machado H, Sackton TB, Schlenke TA, Watada M, Wegmann D* & Singh ND* (2014). Drosophila suzukii: the genetic footprint of a recent, world-wide invasion. Mol Biol Evolution. 31 (12):3148-3163.
    • Dussex N, Wegmann D & Robertson BC (2014). Postglacial expansion and not human influence best explains the population structure in the endangered kea (Nestor notabilis). Mol Ecol 23(9): 2193-2209.
    • Gray M, Wegmann D, Hasl RJ, White MA, Gabriel SI, Searle JB, Cuthbert RJ, Ryan PG & Payseur BA (2014). Demographic history of a recent invasion of house mice on the isolated Island of Gough. Mol Ecol 23 (8): 1923–1939.

    2013

    • Chu JH*, Wegmann D*, Yeh CF, Lin RC, Yang XJ, Lei FM, Yao CT, Zou FS & Li SH (2013). Inferring the geographic mode of speciation by contrasting autosomal and sex-linked genetic diversity. Mol Biol Evol. 30: 2519-2530.

    2011

    • Thalmann O*, Wegmann D*, Spitzner M, Arandjelovic M, Guschanski K, Leuenberger C, Bergl RA and Vigilant L (2011). Historical sampling reveals dramatic demographic changes in western gorilla populations. BMC Evol Biol 11: #85.

    2010

    • Peter B, Wegmann D and Excoffier L (2010). Distinguishing between population bottleneck and population subdivision by a Bayesian model choice procedure. Mol Ecol 19 (21): 4648-4660.
    • Wegmann D and Excoffier L (2010) Bayesian Inference of the Demographic History of Chimpanzees. Mol Biol Evol 27 (6): 1425-1435.


    *order of authroship is arbitrary

  • Humans

    Upcoming

    • Marchi N, Winkelbach L, Schulz I, Brami M, Hofmanová Z, Blöcher J, Reyna-Blanco CS, Diekmann Y, Thiéry A, Kapopoulou A, Link V, Piuz V, Kreutzer S, Figarska S, Ganiatsou E, Pukaj A, Karul N, Gerritsen F, Pechtl J, Peters J, Zeeb-Lanz A, Lenneis E, Teschler-Nicola M, Triantaphyllou S, Stefanović S, Papageorgopoulou C, Wegmann D, Burger J & Excoffier L (2021) The mixed genetic origin of the first farmers of Europe. BioRxiv.
    • Žegarac A, Winkelbach L, Blöcher J, Diekmann Y, Gavrilović MK, Porčić M, Stojković B, Milašinović L, Schreiber M, Wegmann D, Veeramah KR, Stefanović S & Burger J (2020) Kinship, acquired and inherited status, and population structure at the Early Bronze Age Mokrin necropolis in northern Serbia. BioRxiv.

    2021

    • Macháček M , Nedoma R, Dresler P, Schulz I, Lagonike, Johnson SM, Kaňáková L, Slámová A, Llamas B, Wegmann D & Hofmanová Z (2021) Runes from Lány (Czech Republic) - The oldest inscription among Slavs. A new standard for multidisciplinary analysis of runic bones. J. Archaeol. Sci (in press)

    2020

    • Burger J*, Link V*, Blöcher J, Schulz A, Sell C, Pochon Z, Diekmann Y, Žegarac A, Hofmanová Z, Winkelbach L, Reyna-Blanco CS, Bieker V, Orschiedt J, Brinker U, Scheu A, Leuenberger C, Bertino TS, Bollongino R, Lidke G, Stefanović S, Jantzen D, Kaiser W, Terberger TS, Thomas MG, Veeramah KR, Wegmann D (2020) Low Prevalence of Lactase Persistence in Bronze Age Europe Indicates Ongoing Strong Selection over the Last 3,000 Years. Current Biology

    2018

    • Scheib C, Li H, Desai T, Link V, Kendall C, Dewar G, Griffith P, Mörseburg A, Johnson J, Potter A, Kerr S, Endicott P, Lindo J, Haber M, Xue Y, Tyler-Smith C, Sandhu M, Lorenz J, Randall T, Faltyskova Z, Pagani L, Danecek P, O'Connell T, Martz P, Boraas A, Byrd B, Leventhal A, Cambra R, Williamson R, Lesage L, Holguin B, Ygnacio-De Soto E, Rosas J, Metspalu M, Stock J, Manica A, Scally A, Wegmann D, Malhi R & Kivisild T (2018). Ancient human parallel lineages within North America contributed to a coastal expansion. Science 360: 1024--1027.
    • Veeramah K, Rott A, Gross M, van Dorp L, López S, Kirsanow K, Sell C, Blöcher J, Wegmann D, Link V, Hofmanova Z, Peters J, Trautmann B, Gairhos A, Haberstroh J, Päffgen B, Hellenthal G, Haas-Gebhard B, Harbeck M & Burger J (2018). Population genomic analysis of elongated skulls reveals extensive female-biased immigration in early medieval Bavaria. PNAS 115 (13): 3494-3499.

    2017

    • Kousathanas A, Leuenberger C, Link V, Sell C, Burger J & Wegmann D (2017). Inferring heterozygosity from ancient and low coverage genomes. Genetics 205: 317-332.

    2016

    • Broushaki F, Thomas MG, Link V, López S, van Dorp L, Kirsanow K, Hofmanová Z, Diekmann Y, Cassidy LM, Díez-del-Molino D, Kousathanas A, Sell C, Robson HK, Martiniano R, Blöcher J, Scheu A, Kreutzer S, Bollongino R, Bobo D, Davudi H, Munoz O, Currat M, Abdi K, Biglari F, Craig OE, Bradley DG, Shennan S, Veeramah KR, Mashkour M, Wegmann D, Hellenthal G & Burger J (2016). Early neolithic genomes from the eastern Fertile Crescent. Science 353: 499-503.
    • Hofmanová Z, Kreutzer S, Hellenthal G, Sell C, Diekmann Y, Díez del Molino D, van Dorp L, López S, Kousathanas A, Link V, Kirsanow K, Cassidy LM, Martiniano R, Strobel M, Scheu A, Kotsakis K, Halstead P, Triantaphyllou S, Kyparissi-Apostolika N, Urem-Kotsou DC, Ziota C, Adaktylou F, Gopalan S, Bobo DM, Winkelbach L,Blöcher J, Unterländer M, Leuenberger C, Çilingiroglu Ç, Horejs B, Gerritsen F, Shennan S, Bradley DG, Currat M, Veeramah K, Wegmann D, Thomas MG, Papageorgopoulou C & Burger J (2016). Early farmers from across Europe directly descended from Neolithic Aegeans. PNAS 113: 6886-6891.

    2014

    • Zawistowski M, Reppell M, Wegmann D, St Jean PL, Ehm MG, Nelson MR, Novembre J & Zöllner S (2014). Analysis of rare variant population structure in Europeans explains differential stratification of gene-based tests. Eur. J. Hum. Genet. 22: 1137-1144.
    • Wegmann D & Currat M (2014). Recipient of the 2013 Molecular Ecology Prize: Laurent Excoffier. Mol Ecol, 23:16-19. 

    2013

    • Schaibley VM, Zawistowski M, Wegmann D, Ehm MG, Nelson MR, St. Jean PL, Abecasis G, Novembre J, Zöllner S & Li JZ (2013). The influence of genomic context on mutation patterns in the human genome inferred from rare variants. Genome Res. 23: 1974-1984.

    2012

    • Nelson MR*, Wegmann D*, Ehm MG, Kessner D, St. Jean PL, Verzilli C, Shen J, Tang Z, Bacanu SA, Fraser D, Warren L, Aponte J, Zawistowski M, Liu X, Zhang H, Zhang Y, Li J, Li Y, Li L, Woollard P, Topp S, Hall MD, Nangle K, Abecasis G, Wang J, Cardon LR, Zollner S, Whittaker JC, Chissoe SL, Novembre J and Mooser VE (2012). Abundance of rare functional variants in 202 drug target genes found sequencing 14002 people. Science 337: 100-104.
    • Rubio JP, Topp S*, Warren L*, St. Jean PL, Shen J, Wegmann D, Kessner D, Novembre J, Fraser D, Aponte J, Nangle K, Cardon LR, Ehm MG, Chissoe SL, Whittaker JC, Nelson MR and Mooser VE (2012). Deep sequencing of the LRRK2 gene in 14,002 individuals to guide the clinical development of LRRK2 inhibitors. Hum. Mut. 33: 1087-1098.

    2011

    • Veeramah KR, Tönjes A, Kovacs P, Gross A, Wegmann D, Geary P, Gasperikova D, Klimes I, Scholz M, Novembre J and Stumvoll M (2011). Genetic variation in the Sorbs of eastern Germany in the context of broader European genetic diversity. Eur J Human Genet 19: 995-1001.
    • Stahl EA, Wegmann D, Kraft P, Chen R, Kallberg HJ, Kurreeman FAS, Gregersen PK, Alfredsson L, Siminovitch KA, Worthington J, de Bakker PIW, Raychaudhuri S and Plenge RM (2012). Polygenic modeling of genome-wide association study data reveals hidden heritability of rheumatoid arthritis risk. Nat Genet 44: 483.
    • Veeramah KR, Wegmann D, Woerner A, Mendez FL, Watkins JC, Destro-Bisol G, Soodyall H, Louie L and Hammer MF (2011). An early divergence of KhoeSan ancestors from those of other modern humans is supported by an ABC-based analysis of autosomal re-sequencing data. Mol Biol Evol 29: 617-630.
    • Wegmann D, Kessner D, Veeramah KR, Mathias RA, Nicolae DL, Yanek LR, Sun YV, Torgerson DG, Rafaels N, Mosley T, Becker LC, Ruczinski I, Beaty TH, Kardia SLR, Meyers DA, Barnes KC, Becker DM, Freimer N and Novembre J (2011). Recombination rates in admixed individuals identified by ancestry-based inference. Nat Genet 43:9 847-853.

    2010

    • Ray N, Wegmann D , Fagundes NJR, Wang S, Ruiz-Linares A, and Excoffier L (2010). A Statistical Evaluation of Models for the Initial Settlement of the American Continent Emphasizes the Importance of Gene Flow with Asia. Mol Biol Evol 27 (2): 337-345.

    2009

    • Hofer T, Ray N, Wegmann D and Excoffier L (2009) Large allele frequency differences between human continental groups are more likely to have occurred by drift during range expansions than by selection. Ann Hum Genet 73 (1): 95-108.

     

    *order of authroship is arbitrary

  • Stats

    Upcoming

    2020

    2019

    2018

    • Kousathanas A, Duchen P & Wegmann D (2018). A Guide to General-Purpose ABC Software. In Handbook of Approximate Bayesian Computation. Eds. Sisson SA, Fan Y & Beaumont MA. Chapman and Hall/CRC Press.

    2017

    • Link V, Kousathanas A, Veeramah K, Sell C, Scheu A & Wegmann D (2017). ATLAS: Analysis Tools for Low-depth and Ancient Samples. bioRxiv
    • Duchen P, Leuenberger C, Szilagyi SM, Harmon L, Eastman J, Schweizer M & Wegmann D (2017). Inference of evolutionary jumps in large phylogenies using Lévy processes. Systematic Biology 66(6):950–963.
    • Kousathanas A, Leuenberger C, Link V, Sell C, Burger J & Wegmann D (2017). Inferring heterozygosity from ancient and low coverage genomes. Genetics 205: 317-332.
    • Fonseca Costa SS, Wegmann D & Ripperger JA (2017). Normalisation against circadian and age-related disturbances enables robust detection of gene expression changes in liver of aged mice. PLoS ONE 12(1): e0169615.

    2016

    • Kousathanas A, Leuenberger C, Helfer J, Quninodoz M, Foll M & Wegmann D (2016). Likelihood-free inference  in high-dimensional models. Genetics 203(2): 893-904.
    • Ferrer-Admetlla A, Leuenberger C, Jensen JD & Wegmann D (2016). An approximate Markov model for the Wright-Fisher diffusion and its application to time-series data. Genetics 203(2):831-846.

    2013

    • Chu JH*, Wegmann D*, Yeh CF, Lin RC, Yang XJ, Lei FM, Yao CT, Zou FS & Li SH (2013). Inferring the geographic mode of speciation by contrasting autosomal and sex-linked genetic diversity. Mol Biol Evol. 30: 2519-2530.
    • Schaibley VM, Zawistowski M, Wegmann D, Ehm MG, Nelson MR, St. Jean PL, Abecasis G, Novembre J, Zöllner S & Li JZ (2013). The influence of genomic context on mutation patterns in the human genome inferred from rare variants. Genome Res. 23: 1974-1984.

    2012

    • Slater GJ, Harmon LJ, Wegmann D, Joyce P, Revell LJ and Alfaro ME (2012). Fitting models of continuous trait evolution to incompletely sampled comparative data using Approximate Bayesian Computation. Evolution 66: 752-762.

    2011

    • Wegmann D, Kessner D, Veeramah KR, Mathias RA, Nicolae DL, Yanek LR, Sun YV, Torgerson DG, Rafaels N, Mosley T, Becker LC, Ruczinski I, Beaty TH, Kardia SLR, Meyers DA, Barnes KC, Becker DM, Freimer N and Novembre J (2011). Recombination rates in admixed individuals identified by ancestry-based inference. Nat Genet 43:9 847-853.

    2010

    • Peter B, Wegmann D and Excoffier L (2010). Distinguishing between population bottleneck and population subdivision by a Bayesian model choice procedure. Mol Ecol 19 (21): 4648-4660.
    • Wegmann D, Leuenberger C, Neuenschwander S and Excoffier L (2010). ABCtoolbox: a versatile toolkit for approximate Bayesian computations. BMC Bioinformatics 11: 116.
    • Leuenberger C* and Wegmann D* (2010) Bayesian Computation and Model Selection Without Likelihoods. Genetics 184 (1): 243-252.

    2009

    • Wegmann D, Leuenberger C and Excoffier L (2009) Efficient Approximate Bayesian Computation Coupled With Markov Chain Monte Carlo Without Likelihood. Genetics 182 (4): 1207-1218.


    *order of authroship is arbitrary

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