Publications Photonic Nanosystems group
Selected Publications
P. Acuna, F.M. Möller, P. Holzmeister, S. Beater, B. Lalkens and P. Tinnefeld, “Fluorescence Enhancement at Docking Sites of DNA-Directed Self-Assembled Nanoantennas”, Science, 338, pp. 506-510 (2012).
This work was highlighted in Nature Methods, “Dye shines bright”, Nature Chemistry, “Assembling nanoantennas” and Physik Journal, “Fokussieren mit Gold”. Selected for the Faculty of 1000.
P. Acuna, M. Bucher, I.H. Stein, C. Steinhauer, A. Kuzyk, P. Holzmeister, R. Schreiber, A. Moroz, F.D. Stefani, T. Liedl, F.C. Simmel, P. Tinnefeld, “Distance dependence of Single-Fluorophore Quenching by Gold Nanoparticles studied on DNA Origami”, ACS Nano, 6, pp. 3189-3195 (2012).
Puchkova, C. Vietz, E. Pibiri, B. Wünsch, M. Sanz Paz, G. P. Acuna, P. Tinnefeld, “DNA Origami Nanoantennas with over 5000fold Fluorescence Enhancement and Single-Molecule Detection at 25 μM”, Nano Letters, 15 pp. 8354 (2015).
Raab, C. Vietz, F. Stefani, G. P. Acuna, P Tinnefeld, “Single-Molecule Mirage: shifted molecular coupling in a single molecule-mirage”, Nat. Comm., 8 pp. 13966 (2017).
Vietz, I. Kaminska, M. Sanz Paz, P. Tinnefeld, G. P. Acuna, “Broadband Fluorescence Enhancement with Self-Assembled Silver Nanoparticle Optical Antennas”, ACS Nano, 11 pp. 4969 (2017).
For a full list of past publications please follow the following link:
2023
- Super‐Resolved FRET Imaging by Confocal Fluorescence‐Lifetime Single‐Molecule Localization Microscopy
C Zaza, G Chiarelli, LP Zweifel, M Pilo‐Pais, E Sisamakis, F Barachati, ...
Small Methods, 2201565 2023
- Localización de molécula única mediante el escaneo de un mínimo de intensidad
F Edorna, L Masullo, A Szalai, L Lopez, M Pilo-Pais, G Acuna, F Stefani
Libro de Resúmenes XXIII CAFQI 2023
- Fabrication of 3D Oriented MOF Micropatterns with Anisotropic Fluorescent Properties
MJ Velásquez‐Hernández, M Linares‐Moreau, LA Brandner, B Marmiroli, ...
Advanced Materials, 2211478 3 2023
- Ultrasensitive and multiplexed miRNA detection system with DNA-PAINT
S Kocabey, G Chiarelli, GP Acuna, C Ruegg
Biosensors and Bioelectronics 224, 115053 2 2023
- DNA origami assembled nanoantennas for manipulating single-molecule spectral emission
M Sanz-Paz, F Zhu, N Bruder, K Kołątaj, AI Fernández-Domínguez, ...
Nano Letters 2023
- Gold nanorod DNA origami antennas for 3 orders of magnitude fluorescence enhancement in NIR
K Trofymchuk, K Kołątaj, V Glembockyte, F Zhu, GP Acuna, T Liedl, ...
ACS nano 17 (2), 1327-1334 5 2023
2022
- Nanometer resolution imaging and tracking of single fluorophores by sequential structured illumination
P Zdankowski, LF Lopez, GP Acuna, FD Stefani
ACS Photonics 9 (12), 3777-3785 2 2022
- Reconfigurable chirality with achiral excitonic materials in the strong-coupling regime
PE Stamatopoulou, S Droulias, GP Acuna, NA Mortensen, C Tserkezis
Nanoscale 14 (47), 17581-17588 5 2022
- DNA origami book biosensor for multiplex detection of cancer-associated nucleic acids
I Domljanovic, M Loretan, S Kempter, GP Acuna, S Kocabey, C Ruegg
Nanoscale 14 (41), 15432-15441 3 2022
- DNA-Templated Ultracompact Optical Antennas for Unidirectional Single-Molecule Emission
F Zhu, M Sanz-Paz, AI Fernández-Domínguez, X Zhuo, LM Liz-Marzán, ...
Nano Letters 2022 - DNA self-assembly of single molecules with deterministic position and orientation
AK Adamczyk, TAPM Huijben, M Sison, A di Luca, G Chiarelli, S Vanni, ...
arXiv preprint arXiv:2207.06472 2022 - An alternative to MINFLUX that enables nanometer resolution in a confocal microscope
LA Masullo, AM Szalai, LF Lopez, M Pilo-Pais, GP Acuna, FD Stefani
Light: Science & Applications 11 (1), 1-9 1 2022 - Unidirectional ultracompact DNA-templated optical antennas
F Zhu, M Sanz-Paz, A Fernandez-Dominguez, X Zhuo, LM Liz-Marzan, ...
arXiv preprint arXiv:2204.03604 2022 - Optical ultracompact directional antenna based on a dimer nanorod structure
F Zhu, M Sanz-Paz, A Fernandez-Dominguez, M Pilo-Pais, GP Acuna
arXiv preprint arXiv:2204.02347 1 2022 - Correction: An alternative to MINFLUX that enables nanometer resolution in a confocal microscope
LA Masullo, AM Szalai, LF Lopez, M Pilo-Pais, GP Acuna, FD Stefani
Light, Science & Applications 11 2022
2021
- Watching single unmodified enzymes at work
C Ying, E Karakaci, E Bermudez-Urena, A Ianiro, C Foster, S Awasthi, ...
arXiv preprint arXiv:2107.06407 2021 - Determining the in-plane orientation and binding mode of single fluorescent dyes in DNA origami structures
K Hübner, H Joshi, A Aksimentiev, FD Stefani, P Tinnefeld, GP Acuna
ACS nano 15 (3), 5109-5117 2021 - Addressable nanoantennas with cleared hotspots for single-molecule detection on a portable smartphone microscope
K Trofymchuk, V Glembockyte, L Grabenhorst, F Steiner, C Vietz, C Close, ...
Nature communications 12 (1), 1-8 2021 - Nanoscale Advances
GP Acuna, D Garoli
2021 - Three-dimensional total-internal reflection fluorescence nanoscopy with nanometric axial resolution by photometric localization of single molecules
AM Szalai, B Siarry, J Lukin, DJ Williamson, N Unsain, A Cáceres, ...
Nature communications 12 (1), 1-13 2021 - Recent advances in plasmonic nanocavities for single-molecule spectroscopy
N Maccaferri, G Barbillon, AN Koya, G Lu, GP Acuna, D Garoli
Nanoscale Advances 3 (3), 633-642 2021
2020
- In Situ Photothermal Response of Single Gold Nanoparticles through Hyperspectral Imaging Anti-Stokes Thermometry
M Barella, IL Violi, J Gargiulo, LP Martinez, F Goschin, V Guglielmotti, ...
ACS nano 15 (2), 2458-2467 2020 - Self-Assembled Nanoparticle Optical Antennas
K Trofymchuk, GP Acuna, V Glembockyte, P Tinnefeld
21st Century Nanoscience–A Handbook, 8-1-8-14 2020 - Self-Assembled Plasmonic DNA Origami Nanoantennas for Diagnostics Applications with Low-Tech Devices
K Trofymchuk, V Glembockyte, L Grabenhorst, C Close, M Pfeiffer, ...
2020 - DNA origami as emerging technology for the engineering of fluorescent and plasmonic-based biosensors
M Loretan, I Domljanovic, M Lakatos, C Rüegg, GP Acuna
Materials 13 (9), 2185 2020 - Three-dimensional total-internal reflection fluorescence nanoscopy with nanometric axial resolution by photometric localization of single molecules
AM Szalai, B Siarry, J Lukin, DJ Williamson, N Unsain, D Refojo, ...
bioRxiv, 693994
2019
- Directing single-molecule emission with DNA origami-assembled optical antennas
K Hübner, M Pilo-Pais, F Selbach, T Liedl, P Tinnefeld, FD Stefani, ...
Nano Letters 19 (9), 6629-6634 2019 - Distance dependence of single-molecule energy transfer to graphene measured with DNA origami nanopositioners
I Kaminska, J Bohlen, S Rocchetti, F Selbach, GP Acuna, P Tinnefeld
Nano Letters 19 (7), 4257-4262 2019 - DNA‐Mediated Self‐Assembly of Plasmonic Antennas with a Single Quantum Dot in the Hot Spot
F Nicoli, T Zhang, K Hübner, B Jin, F Selbach, G Acuna, C Argyropoulos, ...
Small 15 (26), 1804418 2019 - DNA origami nanotools for single-molecule biosensing and superresolution microscopy
P Tinnefeld, GP Acuna, Q Wei, A Ozcan, C Vietz, B Lalkens, K Trofymchuk, ...
Optical Manipulation and Its Applications, AW5E. 5 2019 - Benchmarking smartphone fluorescence-based microscopy with DNA origami nanobeads: reducing the gap toward single-molecule sensitivity
C Vietz, ML Schütte, Q Wei, L Richter, B Lalkens, A Ozcan, P Tinnefeld, ...
ACS omega 4 (1), 637-642 2019 - Plasmon-assisted Förster resonance energy transfer at the single-molecule level in the moderate quenching regime
J Bohlen, Á Cuartero-González, E Pibiri, D Ruhlandt, ...
Nanoscale 11 (16), 7674-7681
-> see pdf Nano.Letters 2015 15(12), pp8354-8359
P. Holzmeister, E.Pibiri, J.J. Schmied, T. Sen, G.P. Acuna*, P. Tinnefeld(2014)
-> see pdf Nature Communications, 5:5356
- Controlled reduction of photobleaching in DNA origami – gold nanoparticle hybrids
J.V. Pellegrotti, G.P. Acuna*, A. Puchkova, P. Holzmeister, A. Gietl, B. Lalkens, F. Stefani, P. Tinnefeld (2014):
-> see pdf Nano.Letters, 14(5), 2831-2836
- Single-Molecule Positioning in Zeromode Waveguides by DNA Origami Nano-Adapters
E. Pibiri, P. Holzmeister, B. Lalkens, G.P. Acuna*, P. Tinnefled (2014):
-> see pdf Nano.Letters,14(6), 3499–3503
- Breaking the Concentration Limit of Optical Single -Molecule Detection
Holzmeister, G. P. Acuna, D. Grohmann, P. Tinnefeld (2014):
-> see pdf Chem.Soc.Rev., 43(4), 1014-1028 (issue back cover)
- Placing Individual Molecules in the Center of Nanoapertures
S. Heucke, F. Baumann, G.P. Acuna, P.M.D. Severin, S.W. Stahl, M. Strackharn, I.H. Stein, P. Altpeter, P. Tinnefeld,
H.E. Gaub (2014):
-> see pdf Nano Lettres, 14(2), 391-395
2013
Distance Control in-between Plasmonic Nanoparticles via Biological and Polymeric Spacers
X. Yu, D.Y. Lei, F. Amin, R. Hartmann, G.P. Acuna, A. Guerreo-Martinez, S.A. Maier, P. Tinnefeld,
S. Carregal-Romero, W.J. Parak (2013):
-> see pdf Nano Today, 8 (5), 480-493
- Angular Modulation of Single-Molecule Fluorescence by Gold Nanoparticles on DNA Origami Templates
F.M. Möller, P. Holzmeister, T. Sen, G.P. Acuna*, P. Tinnefeld (2013): -
-> see pdf Nanophotonics, 2(3), 167-172
- DNA-Templated Nanoantennas for Single-Molecule Detection at Elevated Concentrations
G.P. Acuna*, P. Holzmeister, F.M. Möller, S. Beater, B. Lalkens, P. Tinnefeld (2013):
-> see pdf Proc. SPIE 8595, online
2012
Fluorescence Enhancement at Docking Sites of DNA-Directed Self-Assembled Nanoantennas
G.P. Acuna*, F.M. Möller, P. Holzmeister, S. Beater, B. Lalkens and P. Tinnefeld (2012):
-> see pdf Science, 338(6106): 506-510
- Distance Dependence of Single-Fluorophore Quenching by Gold Nanoparticles studied on DNA Origami
G.P. Acuna*, M. Bucher, I.H. Stein, C. Steinhauer, A. Kuzyk, P. Holzmeister, R. Schreiber, A. Moroz, F.D. Stefani,
T. Liedl, F.C. Simmel, P. Tinnefeld (2012):
-> see pdf CS Nano, 6, 4, 3189-3195