Yann Ravussin
PD.
Senior Researcher
Medicine Section
Ch. du Musée 5
1700 Fribourg
Biography
The Ravussin laboratory is interested in the physiological and molecular underpinnings of body weight regulation exploring the idea of a body weight setpoint. Both weight loss and weight gain elicit changes in feeding behavior and metabolism that favor the return to previous body weight implying a system in which changes from "normal" body weight are perceived and subsequent adaptations are undertaken. Using surgically implanted feeding tubes, the lab is able to precisely feed animals and explore these changes under various conditions including:
1. overfeeding
2. underfeeding
3. altered feed timing (circadian rhythm)
Research and publications
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ALL PUBLICATIONS
29 publications
Weight Categories, Trajectories, Eating Behavior, and Metabolic Consequences during Pregnancy and Postpartum in Women with GDM
Nutrients (2024) | Journal articleDeletion of the Circadian Clock Gene Per2 in the Whole Body, but Not in Neurons or Astroglia, Affects Sleep in Response to Sleep Deprivation
Clocks & Sleep (2023) | Journal articleAn Overfeeding-Induced Obesity Mouse Model Reveals Necessity for Sin3a in Postnatal Peak β Cell Mass Acquisition
Diabetes (2022) | Journal articleSucrose dampens caffeine-induced blood pressure elevations - A randomized crossover pilot study in healthy, non-obese men.
Frontiers in nutrition (2022) | Journal articleInterindividual variability of human thermoregulation: Toward personalized ergonomics of the indoor thermal environment.
Obesity (Silver Spring, Md.) (2022) | Journal articleErratum: Peroxisomal and microsomal lipid pathways associated with resistance to hepatic steatosis and reduced pro-inflammatory state (Journal of Biological Chemistry (2010) 285 (31011–31023) DOI: 10.1074/jbc.M110.127159)
Journal of Biological Chemistry (2020) | Journal articleA New Symptom of COVID-19: Loss of Taste and Smell
Obesity (2020) | Journal articleEvidence for a Non-leptin System that Defends against Weight Gain in Overfeeding
Cell Metabolism (2018) | Journal articleEnergy homeostasis in leptin deficient Lepob/ob mice
PLoS ONE (2017) | Journal articleWeight perturbation alters leptin signal transduction in a region-specific manner throughout the brain
PLoS ONE (2017) | Journal article